Prep the Roast: Pat the chuck roast dry and season generously with salt, pepper, minced onion, and garlic powder.
Sear the Beef: Heat olive oil in a large Dutch oven over medium-high heat. Sear the roast on all sides until golden brown, about 4 minutes per side. Remove and set aside.
Sauté the Veggies: In the same pot, add carrots, celery, onion, and garlic. Cook until softened, about 5 minutes.
Build the Sauce: Stir in tomato paste and cook for 1-2 minutes. Pour in red wine and beef broth, scraping up any browned bits from the pot. Season with salt and pepper.
Braise the Beef: Return the roast to the pot. Cover and transfer to a preheated oven at 325°F. Braise for 2.5–3 hours, or until beef is fork-tender.
Final Touches: Adjust seasoning if needed. Let the roast rest for 10 minutes before serving.